San Francisco 49ers predictions & odds
Free AI predictions, live bookmaker odds and the full schedule for San Francisco 49ers. Every pick tracked with public win/loss history before each game.
Predictions
Upcoming AI picks
No upcoming picks right now
New AI picks are generated as fixtures approach — check back soon.
Fixtures
Upcoming matches
Rivalries
Top head-to-heads
Public track record
AI prediction record
Hit rate
44%
Record
4–5
Net units
-1.89u
Picks graded
9
Every 49ers pick is graded against the final result — no cherry-picking. See the picks →
The club
About 49ers
49ers
The San Francisco 49ers are a professional American football team based in San Francisco, California, competing in the NFL.
- Founded
- 1946
- Home ground
- Levi's Stadium
- Location
- San Francisco, United States
- Official site
- https://www.49ers.com/ (opens in new tab)
Good to know
Frequently asked questions
What league does San Francisco 49ers play in?
San Francisco 49ers competes in NFL, NFL Preseason, NFL Super Bowl Winner. Follow their matches and predictions on SignalOdds.
When is San Francisco 49ers's next match?
San Francisco 49ers's next scheduled match is against Washington Commanders on October 20, 2026. Check the events section for live odds and AI predictions.
Do you have AI predictions for San Francisco 49ers matches?
When San Francisco 49ers has upcoming matches with available odds, our AI models analyze them and provide predictions with confidence ratings and odds comparisons. Check the predictions section for current picks.
Related teams
Upcoming opponents and other NFL teams
